Biosafety Pdf

Historically, the information in this publication has been advisory in nature even though legislation and regulation, in some circumstances, have overtaken it and made. Do you have PowerPoint slides to share? If so, share your PPT presentation slides online with PowerShow. gaps in biosafety and risk assessment knowledge and expertise in clinical laboratories within the state. The goals of the Biological Safety (or Biosafety) Program are to protect laboratory workers, the public and the environment from potentially hazardous biological materials. Biosafety Level II Handling Practices, Bloodborne Pathogens and Medical Waste: Yes or No UCSB Controlled Substances: Yes or No Autoclave Safety: Yes or No NA. “Biosafety is an inexact science, and the interacting system of agents and activities and the people performing them are constantly changing. These policies and procedures reflect current biosafety regulatory expectations, as well. This document provides guidelines for the design and installation of Class II Type B2 Biological Safety Cabinets at National Institutes of Health facilities. Concepts of biosafety and biosecurity deal with related but distinctly different issues. Biosafety level designations are based on a composite of the design features, construction, containment facilities, equipment, practices and operational procedures required for working with agents from the various risk groups. Setting the stage for a substantively different approach for managing the risks of working with biological agents in laboratories, Laboratory Biorisk Management: Biosafety and Biosecurity introduces the concept of biorisk management—a new paradigm that encompasses both laboratory biosafety and biosecurity. The training ensures that personnel working in certain laboratories have been trained in basic biological safety principals before conducting work in laboratories at Indiana University. Appropriate biosafety regulations are one of the prerequisites for a successful transfer of biotechnology to and, among developing countries. " - WHO web site The 3. Biomedical Waste Training. A combination of procedures, engineering controls, work practices, and policies are utilized to develop these different biosafety levels. 0 ABOUT UCR's BIOSAFETY PROGRAM 1. Biosafety and Health is an open access, peer-reviewed journal sponsored by the Chinese Medical Association, managed by National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC). Alex Isakov, an emergency medicine and EMS physician, who is the medical director for the Emory-Grady EMS Biosafety Transport Program. The laboratory supervisor must ensure that laboratory personnel demonstrate proficiency in standard and special microbiological practices before working with BSL-2 agents. Biological Safety Level (BSL): There are four biosafety levels, BSL 1, 2, 3, or 4, consisting of combinations of laboratory practices and techniques, safety equipment and laboratory facilities. Biological Safety Cabinet Training 7. Panel on Biosafety and the Biosafety & Biosecurity Program have revised this document based on the latest government regulatory requirements, guidelines and current professional standards. Another class is planned to be added in 2017. Structured biological safety programs, mishap risk management, biological risk assessments to determine BSLs, and safety controls protect employees and members of the public from the hazards associated with IAT from microbiological activities. A laboratory-specific biosafety manual must be prepared and adopted as policy. Specific practices for CHESS appear below; general resources are the CDC publication "Biosafety in Microbiological and Biomedical Laboratories (5th Edition)", available here, and the set of EH&S BioSafety Manuals (access restricted to those with a Cornell NetId). 01 The purpose of this policy is to formalize Oklahoma State University’s obligation to ensure that activities involving biohazardous material (as defined below) are conducted safely. Read Quick Tips #327 for classification, practices and primary and secondary barriers. Biosafety is a two way path – to be ‘biosafe’ implies creating a safe working environment for all personnel and ensuring that the work being done does not impact the environment. The biological safety cabinet is the one piece of laboratory and pharmacy equipment that provides protection for personnel, the product, and the environment. Grant UH4 ES027093-01 (Ebola Biosafety and Infectious Disease Response) Clinical Biosafety Awareness Course This one-hour on-line program is taught by Dr. * The Authorities are: a) in England - the Ministry of Agriculture, Fisheries and Food; b) in Scotland - the Scottish Office Agriculture and Fisheries Department and c) in. The book also provides laboratory. If you continue browsing the site, you agree to the use of cookies on this website. AAAS Program on Scientific Freedom, Responsibility and Law. 0 gm Distilled water 1000 ml Mix the ingredients and dissolve them by heating in a steamer. In a BSL2 lab, the biohazard symbol must be posted on the door and on potentially contaminated equipment. BIOSAFETY CABINET SAFE WORK PRATICES • The BSC should be on at all times while in use. BIOSAFETY MANUAL. By extension, biosafety is also meant to ensure the safety of the rest of the medical facility (including other hospital staff and patients), the community, and laboratory staff families and friends. Biosafety regulations of Asia-Pacific countries. The Biosafety Guide and Biosafety Program is applicable to all personnel who are engaged in research or instructional activities where biological materials are used or the potential for exposure to biological materials exists. CRISPR/Cas9 is a very powerful genome editing technology that is currently being used in many research projects. A second equally important facet of the process is documentation of compliance to the standards of good science as set by regulatory bodies. Biosafety level 2 (BSL-2) is appropriate for handling moderate-risk agents that cause human disease of varying severity. In addition to this manual, the National Institutes of Health (NIH) and the MSU Institutional Biosafety Committee (IBC) require the lab to follow BSL procedures as outlined in the BMBL, 5th Edition. California Blvd. The laboratory supervisor must ensure that laboratory personnel demonstrate proficiency in standard and special microbiological practices before working with BSL-2 agents. Biosafety is a well-established concept with a widely-accepted meaning and international guidance on how it is put into practice at the national level. Four biosafety levels increase in safety and security levels as dangers increase. •Biosafety levels 1 and 2 and corresponding work practices and engineering controls. Biosafety Level 2 (BSL2) Examples of BSL2 Agents: Bacillus anthracis, Bordetella pertussis, Brucella spp. FACT SHEET: Biosafety and Biosecurity in the United. The goals of the biosafety program are to protect personnel from exposure to infectious agents, to prevent environmental contamination, to provide an environment for high quality research while maintaining a safe work place, and to comply with applicable federal, state and local requirements. The Cartagena Protocol on Biosafety: An analysis of results AN IISD BRIEFING NOTE1 Introduction When, on January 29, 2000, negotiators from over 130 countries checked out of their Montreal hotel rooms carrying agreed final text of an international agreement on biosafety, nobody was more surprised than the environmental community. biosafety level assignments and associated precautions. SELECTION Purair BIO biological safety cabinets are available in 4 standard sizes. A biosafety plan template is included as an appendix to this safety manual. Created Date: 20151029133009Z. Biosafety Policy Brief, Volume 5 Issue No. BIOSAFETY RISK ASSESSMENT GUIDELINES v. PIs must receive approval from the Biosafety Officer PRIOR to installation, relocation, or removal of biosafety cabinets/laminar flow hoods. The book also provides laboratory. Simple, clearly understandable illustrations, correct and up to date information's are the main features of this book. Introduction to Biological Safety The Introduction to iological Safety course is a “Self-Enrol” course. Biosafety Outreach Fort Detrick (1943 ‐1969) • Created the Biological Safety Conference in 1956 • Provided guidance to federal agencies in support of the development of biosafety programs and guidelines • Published papers on biosafety practices, risk assessments, and applied research projects. Bloodborne Pathogen Training 6. The UConn Biological Safety Manual will be referred to as “the Manual” throughout this document. Appropriate biosafety regulations are one of the prerequisites for a successful transfer of biotechnology to and, among developing countries. The biosafety plan is a single document that acts as a specific biosafety manual for that permit holder. BIOSAFETY LEVEL 2 • Biosafety level 2 is similar to Biosafety level 1 and is suitable for work involving agents of moderate potential hazard to personnel and the environment. To allow more clarity and a better understanding of the biosafety requirements and recommendations in laboratory animal facilities, various concerns on personal protection and biosafety equipment, facility design, working practices and waste management are addressed in this document, mainly with respect to small animal facilities. Biosafety Consultants. Biosafety level 2 (BSL2) guidelines for teaching laboratories. The mechanism of monitoring and implementation of the National Biosafety Guidelines is built on the following three tiers as specified in the Biosafety Rules, 2005. Biosafety in Microbiological and Biomedical Laboratories (BMBL) quickly became the cornerstone of biosafety practice and policy in the United States upon first publication in 1984. Both routes are supported by dampers that regu-late rate of flow of air. In a BSL2 lab, the biohazard symbol must be posted on the door and on potentially contaminated equipment. When properly installed and certified, the biological safety cabinets (BSC)s listed in the table below may be used for work in BSL 1, BSL 2 and BSL 3 laboratories. Three kinds of biological safety cabinets, designated as Class I, II and III, have been developed to meet varying research and clinical needs. Submissions are reviewed by the IBC for accordance with the guidelines set forth by the National Institutes of Health (NIH). Biosafety Level 1 BSL-1 is appropriate for working with microorganisms that are not known to cause disease in healthy human humans. global biosafety, 2010 Regional Biosafety Awareness Raising Meetings for animal health and public health communities 3 days develop regional action plan for follow up Strengthen biosafety interface between animal and human health (OIE/FAO/WHO) strengthen collaboration as biosafety is of mutual concern. 1, Wednesday, 7 February 2007 3 including the safe development and application of biotechnology (Programme 1. T h e p o r t i o n s a f f e c t e d b y t h i s R A R a r e l i s t e d i n t h e s u m m a r y o f change. Table of Contents Foreword Chapter 1: Introduction The Occurrence of Laboratory-Associated Infections Evolution of National Biosafety Guidelines Risk Criteria For Establishing Ascending Levels Of Containment Agent Summary Statements Biosecurity Using BMBL Looking Ahead References Chapter 2: Biological Risk Assessment Hazardous …. Status of Biotechnology Policies and Biosafety Legislation in the COMESA Region - Revised Margaret Karembu, David Wafula, Michael Waithaka and Getachew Belay About ISAAA The International Service for the Acquisition of Agri-biotech Applications (ISAAA) is a non-profit making international network founded in 1990 to. 5 Yes No N/ A. Example: E. The focus of the IHR text largely revolves around outbreak protocol, surveillance, reporting, and capacity building; however, there is surprisingly little mention of laboratory safety concerns. All BSC biological safety cabinets share operational attributes from the compact 3 foot cabinet to the wide-profile 6 foot cabinet. The University of Connecticut (UConn) Biological Safety Manual was written by the Division of Environmental Health and Safety (EHS) and applies to all UConn campuses excluding UConn Health in Farmington. The Stanford biosafety representative can provide assistance. The Biosafety e-Manual outlines procedures for using and disposing of agents and materials handled at Biosafety Level 2 (BSL-2). in work with agents assigned to biosafety levels 1, 2, 3, or 4. University of Saskatchewan Biosafety Cabinet Guideline 2019 Page 2 1 Introduction Biological safety cabinets (BSCs) provide effective primary containment for work with infectious materials or toxins when they are properly maintained and used in conjunction with good microbiological laboratory practices. The Biosafety e-Manual automatically integrates PI-specific information from the PI's Inventory and Activity Registration (IAR) into the existing Biosafety Manual template, creating one document that streamlines and simplifies biosafety compliance efforts across the research community. A laboratory-specific biosafety manual must be prepared and adopted as policy. The device must not be operated as a Class II biological safety cabinet if:. ( more … If you need research compliance or biosafety training, see our site for a comprehensive list of training courses. The Institutional Biosafety Officer (IBSO) is an EHRS Associate Director and is responsible for oversight and daily implementation of the Biosafety Program. Biosafety Considerations for Research with Lentiviral Vectors Recombinant DNA Advisory Committee (RAC) Guidance Document Background: The use of lentiviral vectors has been increasing because the vector system has attractive features; however, such research also raises biosafety issues. Biosafety training is mandatory for researcher and employees prior to initiating works with agents classified at Biosafety Levels 1 &2 BL 1 agents are not associated with disease in adult human, but increased precaution may be appropriate. View PDF (1. 2 Yes No N/ C. Animal Handler Risk Assessment Form (PDF) GWUMC ARF Occupational Health Questionnaire (PDF) ALL Completed FORMS should be submitted to Animal Research Facilities-ARF. Biosafety Outreach Fort Detrick (1943 ‐1969) • Created the Biological Safety Conference in 1956 • Provided guidance to federal agencies in support of the development of biosafety programs and guidelines • Published papers on biosafety practices, risk assessments, and applied research projects. How Biological Safety Cabinets Are Classified. Historically, the information in this publication has been advisory is nature even though legislation and regulation. committees (IBC), animal care and use committees, biological safety professionals, and laboratory animal veterinarians share in this responsibility. particular, biological safety are important international issues. Biosafety levels and Cabinet in laboratory Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Working with our experienced EHS consultants makes it easy to stay compliant – and stay safe. the use of biosafety cabinets, etc. The Class II cabinet is commonly known as a laminar airflow Biological Safety Cabinet. The Institutional Biosafety Committee (IBC) must review and approve all research and teaching projects involving hazardous biological materials, including: Recombinant DNA (as defined by the NIH Guidelines and including transgenic animals and plants) Select Agents (defined by 42 CFR Part 73, 9 CFR Part 121 and 7 CFR Part 331). Visit us at www. General Microbiology Fact Sheet (PDF, 3. to assess the biosafety measures that they have in place. requirement of an institution-appointed Biosafety Officer as described in the NIH Guidelines Section IV-B-3. Animal Handler Risk Assessment Form (PDF) GWUMC ARF Occupational Health Questionnaire (PDF) ALL Completed FORMS should be submitted to Animal Research Facilities-ARF. (2009) or “BMBL” outlines biological safety levels (BSLs), which are distinct from risk group levels. This program has. Once a risk assessment has been documented for the work, then safety controls can be applied to the. Spill in Laboratory. with this Biosafety Manual, the procedures recommended in the CDC/NIH publication Biosafety in Microbiological and Biomedical Labs , and the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules (NIH Guidelines). With Thermo Scientific biological safety cabinets, the certified performance and protection you get on Day 1 stays with you every day in the lab. 1C and the other guidance documents in the DOE G 151. This booklet contains the text of the Cartagena Protocol on Biosafety to the Convention on Biological Diversity, which starts on page 2. Visiting students and scholars without a HawkID or password may get this to complete their ICON training. All of the air from the cabinet is exhausted through a HEPA filter either into the laboratory or to the outside. Biological Safety Office of Risk Management and Safety The Texas A&M University System 2. •Conceptualized by NEPAD Consolidated Plan of Action • Freedom to Innovate-iotechnology in Africa’s Development, Report of the High-Level African Panel on Modern. Biosafety is the discipline that addresses the safe handling and containment of infectious microorganisms to protect workers, the public, agriculture, and the environment from exposure to biological agents or materials that may cause disease or other detrimental effects in humans, plants, or animals. LABORATORY SAFETY TRAINING VA PORTLAND HEALTH CARE SYSTEM RESEARCH AND DEVELOPMENT SERVICE Once you have completed all of the sections, there will be a short test for you to complete. Laboratory work of the type described in this Terrestrial Manual should be carried out with a minimum of risk to the health of the staff (biosafety) and the environment (biocontainment). Pasadena, CA 91125. Created Date: 20151029133009Z. The Biosafety Officer develops and (BSO) conducts appropriate training programs to promote techniques for the safe handling and. to publish biosafety guidelines for protecting workers and preventing exposures in biological laboratories. Laboratory Safety Biosafety Cabinets (BSCs) Properly maintained Biosafety Cabinets (BSCs), when used in conjunction with good microbiological techniques, provide an effective containment system for safe manip - ulation of moderate- and high-risk infectious agents [Biosafety Level 2 (BSL-2) and 3 (BSL-3) agents]. ( more … If you need research compliance or biosafety training, see our site for a comprehensive list of training courses. Harvard Biosafety Manual 2016 Page 3 Introduction and Roles of Key University Personnel. Introduction. PIs must receive approval from the Biosafety Officer PRIOR to installation, relocation, or removal of biosafety cabinets/laminar flow hoods. Biological safety cabinets & clean benches categories. Biohazard Symbol (PDF) Laboratory Biohazard-No Food or Drink (PDF) Laboratory Biohazard- Authorized Personnel Only (PDF) Laboratory Biohazard Sign (PDF). The person laboratory biosafety manual 5th edition may have several name. • Use biological safety cabinets for containment whenever procedures have the potential to generate aerosol droplets. The set of measures taken to. 655/2009; NOW, THEREFORE, in accordance with Article 55(1) of the Constitution of the Federal Democratic Republic of Ethiopia, it is hereby proclaimed as follows: 1. edu Page 4 of 41 1. The campus biosafety officer oversees the program and coordinates the activities of the university’s biosafety committee. National Biosafety Month 2019-Beyond the Lab: Increasing the Visibility of Biosafety and Biosecurity October 14, 2019 The Biosafety Office is excited to announce that October 2019 is National Biosafety Month. Documentation of this certification must be posted in the lab near or on the hood and kept on file by the Biosafety Officer. Specific practices for CHESS appear below; general resources are the CDC publication "Biosafety in Microbiological and Biomedical Laboratories (5th Edition)", available here, and the set of EH&S BioSafety Manuals (access restricted to those with a Cornell NetId). com, Elsevier’s leading platform of peer-reviewed scholarly literature. Biosafety Manual for Molecular Oncology Laboratory 3 precautions to prevent exposures, and the exposure evaluation procedures. The current standard, as have previous versions, states that the use of UV lights. ) 1 BMBL Introduction 1941 - Meyer and Eddie +74 lab associated brucellosis infections in US 1949 - Sulkin and Pike. Work may be done on an open bench top, and containment is achieved through the use of practices normally employed in a basic microbiology laboratory. The American Biological Safety Association attempts a definition by explaining what biosafety encompasses. A Class I or Class II biological safety cabinet is highly recommended for work involving these agents. d Yes No N/ A. Complete Sections 1 and 2 and forward to REHS via email to: [email protected] U of L Institutional Biosafety Committee, or DEHS Biosafety Program. to publish biosafety guidelines for protecting workers and preventing exposures in biological laboratories. As a reminder, National Biosafety Stewardship Month is a period during which institutions are encouraged to reinforce their attention to biosafety policies, practices and. This manual (Biosafety Protocol) has been developed as part of Stevens Institute of Technology’s Biosafety program. OF THE NATIONAL SCIENCE AND TECHNOLOGY COUNCIL JANUARY 2017. Biosafety Level 2 (BSL2) Examples of BSL2 Agents: Bacillus anthracis, Bordetella pertussis, Brucella spp. Biosafety level 2 (BSL2) guidelines for teaching laboratories. The Biological Safety Guide has been developed by the Stevens Institute of Technology’s Environmental Health and Safety Department. Biosafety practices are used in the proper handling of biohazardous organisms. • Add ~250mL water to bag before closing. Introduction Lentiviruses, a genus of the Retroviridae family, are enveloped retroviruses that replicate in a host cell through reverse transcription. Visiting students and scholars without a HawkID or password may get this to complete their ICON training. These may react with organic materials such as paper, cloth, or oil resulting in an explosion. The default biological safety containment level for recombinant viruses is BSL 2 / ABSL 2; however, there are exceptions. Research involving organisms inRisk Group s 3 and 4 is NOT permitted at the University of Houston. Principles of Biosafety The term containment describes safe methods, or properly managing infectious agents in the laboratory environment where they are being handled or maintained. These correlate to but are not equivalent to biosafety levels. Submissions are reviewed by the IBC for accordance with the guidelines set forth by the National Institutes of Health (NIH). ASEAN Biosafety Network Meeting 22-23 May 2017 Nonthaburi, Thailand Biosafety and Biosecurity are global concerns and these issues have been stated in both the WHO International Health Regulation s and the Global Health Security Agenda (GHSA). Environmental Health & Safety > Our Services > Biosafety > Biosafety Manual Biosafety Manual The University of Toronto Biosafety Program is designed to protect lab personnel and the public from potential exposure to biological materials used within the University and to prevent unintentional release into the environment. Check the Training Calendar/Register. All Forma Biological Safety Cabinets are ergonomically designed for maximum safety and comfort for lab personnel. Biosafety Program University of Colorado Laboratory Biosafety Checklist A. This biosafety staff member conducts rDNA/IACUC protocol congruency reviews. Pipetting of BSL-2 materials should be done in a biosafety cabinet. This RAR is effective 8 F e b r u a r y 2 0 1 3. primary containment (e. Four biosafety levels increase in safety and security levels as dangers increase. This Biosafety Manual is applicable to all laboratory, research, teaching, service, and support activities that may involveexposure to biohazard agents or materials ous or otherwisecomes under the purview of the Institutional Biosafety Committee (IBC) at the University of Montana. Preamble: Educators need to be aware of the risks inherent in using microorganisms in the laboratory and must use best practices to minimize the risk to themselves, students, and the community. ENDY 10 Biosafety for Microorganisms Transmitted Primarily by the Airborne Route / 209 MICHAEL A. To address this need, the Committee has developed and approved a Post Approval Laboratory Biosafety Assessment (PDF) process. Biosafety in Microbiological and Biomedical Laboratories (BMBL) quickly became the cornerstone of biosafety practice and policy in the United States upon first publication in 1984. Phone: 206. coli nonpathogenic laboratory strain and S. The IBC meets monthly for convened review of 64% of initial submissions and 5% of amendments. Biosafety level 1 (BSL-1) is the basic level of protection and is appropriate for agents that are not known to cause disease in normal, healthy humans. Louis encephalitis virus, and Coxiella burnetii. Through the history of laboratory-acquired infections from the earliest published case to the emergence of hepatitis B and AIDS, the need for. The book also provides laboratory. Conserving resources in these tight economic times is critical to satisfying pressing Department mission needs. Biohazard Symbol (PDF) Laboratory Biohazard-No Food or Drink (PDF) Laboratory Biohazard- Authorized Personnel Only (PDF) Laboratory Biohazard Sign (PDF). this publication for use in its laboratory procedure manual at a single site. If you wish to import a biological agent that is not listed on your U of T biosafety certificate, an amendment to your certificate must be approved before applying to import. 1201-1221 [Medical Waste. Biosafety training is mandatory for researcher and employees prior to initiating works with agents classified at Biosafety Levels 1 &2 BL 1 agents are not associated with disease in adult human, but increased precaution may be appropriate. •Biosafety levels 1 and 2 and corresponding work practices and engineering controls. REGULATIONS FOR BIOSAFETY AND BIOCONTAINMENT. The Manual has been developed by the IBC for use by principal investigators (PIs) in research; However, it covers all teaching faculty, staff and students, and any nonUniversity personnel who -. The Centers for Disease Control and Prevention (CDC) and the National Institutes of Health (NIH) are our main sources for biological safety information for infectious agents. When properly installed and certified, the biological safety cabinets (BSC)s listed in the table below may be used for work in BSL 1, BSL 2 and BSL 3 laboratories. PENTELLA, PAMELAA. View and Download Esco Class II user and service manual online. Price and D. Biosafety Program University of Colorado Laboratory Biosafety Checklist A. ☐ ☐ ☐ ☐ Are Safety Data Sheets (SDSs) available? Obtain SDSs for hazardous materials in the work area, and make them readily available to personnel. For BSL labs, extra caution must be taken in order to prevent the spread of contaminants from room to room and to the outside environment. Biosafety refers to containment principles, technologies and practices that are implemented to prevent unintentional exposure to pathogens and toxins, or their accidental release into the environment. All PHCbi biosafety cabinets provide biological containment protection for both operator and product proven by an independent test. Unfortunately, due to frequent draughts, the maize crops often fail, leading farmers to huge losses and leaving thousands of people without the they desperately need. Our team of credentialed biosafety professionals, scientists, and engineers has over 50 years’ cumulative experience supporting the stand up, expansion of capabilities, and audits and inspections of A/BSL-1, -2, -3, and -4 facilities in the US and abroad. 131-137 [Special Waste from Health Care-Related Facilities]; 30 TAC §330. Biological Safety Cabinets BSCs are designed to provide personnel, environmental and product protection when appropriate practices and procedures are followed. Biotechnology offers exceptional opportunities to meet the growing needs of food and feed security by enhancing productivity, profitability and environmental sustainability of farming systems. The Cartagena Protocol on Biosafety: An analysis of results AN IISD BRIEFING NOTE1 Introduction When, on January 29, 2000, negotiators from over 130 countries checked out of their Montreal hotel rooms carrying agreed final text of an international agreement on biosafety, nobody was more surprised than the environmental community. Biosafety and Health is an open access, peer-reviewed journal sponsored by the Chinese Medical Association, managed by National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC). GILCHRIST 11 Cell Lines: Applications and Biosafety / 221 OTTO DOBLHOFF-DIER AND GLYN STACEY 12 Allergens of Animal and Biological. Environmental Health and Safety Department. , cell cultures, microbiological stocks) being manipulated inside the cabinet. ABSA International (ABSA) was founded in 1984 to promote biosafety as a scientific discipline and serve the growing needs of biosafety professionals throughout. 896/2015 A PROCLAMATION TO AMEND THE BIOSAFETY PROCLAMATION WHEREAS, it has become necessary to amend the Biosafety Proclamation No. , a well-designed, functional laboratory), and a basic level of operational practices (e. Canadian biosafety guidelines Guides to biosafety plans, handling, best practices and more in Canada. Caltech Environment, Health, and Safety Office. Visiting students and scholars without a HawkID or password may get this to complete their ICON training. BSL2 Training 9. Biosafety Office. Check √ the organism(s) or viruses used in your laboratory :. Occupational Health and Wellness administers the medical surveillance program. 18 National Biotechnology and Biosafety Bill 2012 THE NATIONAL BIOTECHNOLOGY AND BIOSAFETY BILL, 2012 MEMORANDUM. Four biosafety levels increase in safety and security levels as dangers increase. Biosafety Risk Assessment Methodology Susan Caskey*, Jennifer Gaudioso Shigematsu ++, George Risi+++ Esmeralda Prat** Prepared by Sandia National Laboratories Albuquerque, New Mexico 87185 and Livermore, California 94550 Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned. Animal Biosafety Levels. Institutional Biosafety Manual, Version 10-2016 Page 6 of 53. Complete the attached approval form and fax to the Biosafety Officer at 348-3574. Four biosafety levels, referred to as Biosafety Level (BL)1 - Plants (P), BL2-P, BL3-P, and BL4-P, are established in Appendix P of the NIH Guidelines and BL1-P, BL2-P, and BL3-P are summarized in this Manual. The LabGard® ES (Energy Saver) AIR Limited Model NU-545 Biological Safety Cabinet (BSC) is a primary engineering control in obtaining the optimum product quality while reducing the potential for exposure of both product and personnel to airborne biological or particulate chemical agents in low to moderate risk-hazard research and drug preparation or product operations, as prescribed by the. The Biological Safety Office has developed these resources based on guidelines developed by the Center for Disease Control (CDC) and the National Institute of Health (NIH), Biosafety in Microbiological and Biomedical Laboratories (5th edition); 2009, (BMBL), with the endorsement of the University's Biological Safety Committee. Biological Safety Cabinets BSCs are designed to provide personnel, environmental and product protection when appropriate practices and procedures are followed. " This form can be downloaded as a fillable PDF form found on the EHS website at. Historically, the information in this publication has been advisory in nature even though legislation and regulation, in some circumstances, have overtaken it and made. The goals of the biosafety program are to protect personnel from exposure to infectious agents, to prevent environmental contamination, to provide an environment for high quality research while maintaining a safe work place, and to comply with applicable federal, state and local requirements. the researchers is must so that biological safety can be well taken care at the grass root level [3]. }, author={Sunil Kumar Gupta and J. ( more … If you need research compliance or biosafety training, see our site for a comprehensive list of training courses. Biotechnology offers exceptional opportunities to meet the growing needs of food and feed security by enhancing productivity, profitability and environmental sustainability of farming systems. committees (IBC), animal care and use committees, biological safety professionals, and laboratory animal veterinarians share in this responsibility. He co-edited the first two editions of the BMBL, whose guidelines are now accepted as. Biological safety (or biosafety) is primarily the application of concepts relating to risk assessment, personal protective equipments, engineering controls, policies, and preventive measures to promote safe laboratory practices, procedures, and the proper use of containment equipment and facilities. Historically, the information in this publication has been advisory is nature even though legislation and regulation. Richardson was a pioneer in and ceaseless advocate for biological safety and education. Principles of Biosafety The term containment describes safe methods, or properly managing infectious agents in the laboratory environment where they are being handled or maintained. 95677 Fax; (916) 652-8020 WebSite; www. biosafety level assignments and associated precautions. (PI) but is shared with the Institutional Biosafety Committee (IBC), biosafety professionals, laboratory staff and other stakeholders which may include lab animal veterinarians and caretakers, farm staff, operations staff, occupational health practitioners, etc. BIOSAFETY GUIDELINES AND STANDARDS The CDC/NIH Biosafety in Microbiological and Biomedical Laboratories, 5th Edition, the OSHA Occupational Exposure to Bloodborne Pathogens Standard, and the NIH Guidelines involving Research with Recombinant DNA Molecules are most often referred to for the biomedical research that is conducted at DU. Biosafety Committee (IBC). The biosafety plan is a single document that acts as a specific biosafety manual for that permit holder. Personal Protective Equipment (PPE) for Biosafety Labs Biosafety Level → BSL 1 BSL 2 Face Protective eyewear shall be worn for conduct of procedures in which splashes of microorganisms or other hazardous materials are possible. If you continue browsing the site, you agree to the use of cookies on this website. Louis encephalitis virus, and Coxiella burnetii. Certification: The Biological Safety Officer shall coordinate and maintain records of the annual certification of biological safety cabinets. “biosafety” means the avoidance of risk to human health and safety, and the conservation of the environment, as a result of the use of genetically modified organisms;. Concepts of biosafety and biosecurity deal with related but distinctly different issues. Complete the attached approval form and fax to the Biosafety Officer at 348-3574. Horizontal flow clean benches are used worldwide to provide product or sample protection for applications that do not require personal or environmental protection. Biosafety Guidelines. Select Agent Program. Awareness and biosafety and biosecurity culture (documents prepared by FESAP) Fact Sheet on United States Government Culture of Biosafety, Biosecurity, and Responsible Conduct in the Life Sciences 1-bioculture-factsheet_508. Safe biological research includes appropriate facilities and equipment, adequate training, proper laboratory practices and safe working conditions. The four biosafety levels corresponds to four risk groups. Biosafety Cabinet and Animal Transfer Station Use: Biosafety cabinets or animal transfer stations are provided in most animal rooms that have ventilated caging. This publication is a rapid action revision (RAR). The Biosafety e-Manual outlines procedures for using and disposing of agents and materials handled at Biosafety Level 2 (BSL-2). It is an integrated approach to encompassing information on different aspects of bioethics and biosafety and their applications in biotechnology. The objectives of this project were to: 1) assess the uniform application of biosafety and biosecurity policy and directives, plans, orders, and guidance across DoD Component laboratories that were conducting research using. California Institute of Technology. Biosafety and the NIH Guidelines This section will explore: •Why the NIH Guidelines are important •The definition of recombinant or synthetic nucleic acid research Content of the NIH Guidelines Section IV – Roles and Responsibilities •What is an IBC and its function? •How to submit a research proposal to the IBC for review 1. Historically, the information in this publication has been advisory is nature even though legislation and regulation. To protect workers from pathogens and instruments that come in contact with them, they must be disposed of properly in biosafety containers. Biosafety refers to practices and procedures designed to provide safe environments for individuals who work with potentially hazardous biological materials in laboratory environments. The Biological Safety program is designed to maintain safe conditions in biological research and prevent harm to humans, animals and the environment. Biosafety Cabinet Construction Certification All welds, gaskets, plenum penetrations and seals will hold pressure within 10% for 30 minutes or be free of soap bubbles after sealed cabinet is pressurized with compressed air to 2" water gauge. Evaluation of DoD Biological Safety and Security Implementation. 2), and building a common African strategy for biotechnology (Programme 5. d Yes No N/ A. To allow more clarity and a better understanding of the biosafety requirements and recommendations in laboratory animal facilities, various concerns on personal protection and biosafety equipment, facility design, working practices and waste management are addressed in this document, mainly with respect to small animal facilities. 1, 2013 Articles Abstract Biosafety Level Two Plus (BSL-2+) is a term frequently used to describe laboratories where work with microorganisms is conducted in a BSL-2 laboratory with biosafety practices and procedures typically found at BSL-3. Only a few alterations have been made, especially in the text concerning decontamination and inacti-vation. This policy establishes responsibility for the proper use of biohazardous agents, potentially hazardous human materials, and recombinant DNA molecules in research and other educational activities at the University of North Texas (UNT) in order to protect students,. Biological Safety Cabinet Training 7. 2200 for guidance. edu Page 4 of 41 1. •Biosafety or biohazard control is a team effort involving the Principal Investigator (PI), research lab personnel, Institutional Biosafety Committee (IBC), Institutional Review Board (IRB), Institutional Animal Care and Use Committee (IACUC), and Environmental Health. 10Special note should be taken that BSL-4 agents should only be used in Maximum Containment Laboratories and that Class I and Class II biosafety cabinets are only acceptable in Maximum Containment Laboratories with positive pressure containment suits. The Biosafety and Infectious Waste Safety Procedures in this document have been established by Bowling Green State University to comply with Ohio’s Public Employee Risk Reduction Act, the U. (a) any subsequent release activity for the purposes in items 2. safety with respect to the effects of biological research on humans and the environment…. com, Elsevier’s leading platform of peer-reviewed scholarly literature. 13 The primary goal of a Biosafety risk assessment is to identify and mitigate risk. •Biosafety applies to pathogenic or potentially pathogenic biological materials or toxins. The default biological safety containment level for recombinant viruses is BSL 2 / ABSL 2; however, there are exceptions. This Biosafety Manual is applicable to all laboratory, research, teaching, service, and support activities that may involveexposure to biohazard agents or materials ous or otherwisecomes under the purview of the Institutional Biosafety Committee (IBC) at the University of Montana. 9 Yes No N/ A. Risk assessment is a process used to identify the hazardous characteristics of a known infectious or potentially infectious agent or material, the activities that can result in a person’s. Note: The only official copy of this document is on the U of A EHS website. Historically, the information in this publication has been advisory is nature even though legislation and regulation. with this Biosafety Manual, the procedures recommended in the CDC/NIH publication Biosafety in Microbiological and Biomedical Labs , and the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules (NIH Guidelines). All items potentially contaminated with BSL2 materials must be autoclaved or chemically disinfected before they are disposed ofe. Laboratory Biosafety Level Criteria – Biosafety Level 1 28 Section IV Laboratory Biosafety Level Criteria The essential elements of the four biosafety levels for activities involving infectious microorganisms and laboratory animals are summarized in Table 1 of this section and discussed in Section 2. 10 Yes No N/ BSL-2 Audit Checklist (Citation numbers refer to BMBL sections in the BSL-2 criteria) Sharps containers are labeled, conveniently located, and puncture resistant. The IBC meets monthly for convened review of 64% of initial submissions and 5% of amendments. The IBC uses the biosafety levels recommended by the CDC and NIH as the usual standards of containment to be set for work with a given biohazardous material. administrative biosafety, regulations, and selected biosafety activities to faculty, staff, and students working with biohazardous materials. BIOLOGICAL SAFETY PROGRAM a. biosafety equipment such as biological safety cabinets or high efficiency particulate air filtered enclosures are determined as part of the Biosafety Program Permit risk assessment. To address this need, the Committee has developed and approved a Post Approval Laboratory Biosafety Assessment (PDF) process. The IBSO is responsible for compliance with all federal, state, and local regulations that apply to biosafety and keep University regulations up to date. University of Guelph - Biosafety Manual 2nd Ed. Biological safety. The National Institutes of Health is pleased to announce October 2015 as National Biosafety Stewardship Month. Report accidents or incidents involving personal security. The biological safety cabinet is the principal device used to provide containment of infectious aerosols generated by many microbiological procedures. Occupational Health and Wellness administers the medical surveillance program. Yale University Biosafety Manual – May 2017. administrative controls is referred to as biosafety or biohazard control. The terms biological safety cabinet and biosafety cabinet have been widely used to describe a variety of containment devices equipped with HEPA filter(s), designed to provide personnel or both personnel and product protection from biohazardous materials. The laboratory also features a dedicated supply and exhaust air, as well as vacuum lines and decontamination systems. Biosafety Level Classification. facilities as basic – Biosafety Level 1, basic – Biosafety Level 2, containment – Biosafety Level 3 and maximum containment – Biosafety Level 4. Occasionally, when it is impractical to work in BSCs, personal protective equipment, such as laboratory coats and gloves may act as the primary barrier between personnel and infectious materials. " - WHO web site The 3 rd. 64E-16, requires any personnel who works in a Biological Safety Level 2 laboratory or in a laboratory which generates any solid or liquid waste presenting a threat of infection to humans to have Biomedical Waste Training.